diff --git a/src/ripple/app/misc/impl/Manifest.cpp b/src/ripple/app/misc/impl/Manifest.cpp
index 44e19244a..ea2a80e8d 100644
--- a/src/ripple/app/misc/impl/Manifest.cpp
+++ b/src/ripple/app/misc/impl/Manifest.cpp
@@ -471,6 +471,10 @@ ManifestCache::applyManifest(Manifest m)
 
         auto masterKey = m.masterKey;
         map_.emplace(std::move(masterKey), std::move(m));
+
+        // Increment sequence to invalidate cached manifest messages
+        seq_++;
+
         return ManifestDisposition::accepted;
     }