diff --git a/.github/scripts/strategy-matrix/generate.py b/.github/scripts/strategy-matrix/generate.py
index e32e387f2e..8b53109aad 100755
--- a/.github/scripts/strategy-matrix/generate.py
+++ b/.github/scripts/strategy-matrix/generate.py
@@ -180,11 +180,12 @@ def generate_strategy_matrix(all: bool, config: Config) -> list:
                 # shared_linker_flags += '-static-libubsan -static-libasan -static-libtsan'
 
             if architecture['platform'] == 'linux/amd64':
-                # Add -mcmodel=medium to both compiler AND linker flags
+                # Add -mcmodel=medium and -fPIC to both compiler AND linker flags
                 # This is needed because sanitizers create very large binaries
-                cxx_flags += ' -mcmodel=medium'
-                exe_linker_flags+='-mcmodel=medium'
-                shared_linker_flags += '-mcmodel=medium'
+                # -fPIC enables position independent code to avoid relocation range issues
+                cxx_flags += ' -mcmodel=medium -fPIC'
+                exe_linker_flags+='-mcmodel=medium -fPIC'
+                shared_linker_flags += '-mcmodel=medium -fPIC'
 
             if "-O0" in cxx_flags:
                 cxx_flags = cxx_flags.replace("-O0", "-O1")
diff --git a/conan/profiles/sanitizers b/conan/profiles/sanitizers
index cb79455412..670dd1b8b4 100644
--- a/conan/profiles/sanitizers
+++ b/conan/profiles/sanitizers
@@ -12,29 +12,29 @@ tools.info.package_ids:confs+=["user.package:sanitizers"]
 
 {% if sanitizers == "Address" %}
 tools.build:cxxflags+=['-fsanitize=address,undefined,float-divide-by-zero,signed-integer-overflow
--fno-omit-frame-pointer -fno-var-tracking-assignments -O1 -Wno-stringop-overflow -mcmodel=medium']
-tools.build:sharedlinkflags+=['-mcmodel=medium']
-tools.build:exelinkflags+=['-mcmodel=medium']
+-fno-omit-frame-pointer -fno-var-tracking-assignments -O1 -Wno-stringop-overflow -mcmodel=medium -fPIC']
+tools.build:sharedlinkflags+=['-mcmodel=medium -fPIC']
+tools.build:exelinkflags+=['-mcmodel=medium -fPIC']
 {% elif sanitizers == "Thread" %}
 tools.build:cxxflags+=['-fsanitize=thread,undefined,float-divide-by-zero,signed-integer-overflow -fno-omit-frame-pointer
 -fno-var-tracking-assignments
--O1 -Wno-stringop-overflow -Wno-tsan -mcmodel=medium']
-tools.build:sharedlinkflags+=['-mcmodel=medium']
-tools.build:exelinkflags+=['-mcmodel=medium']
+-O1 -Wno-stringop-overflow -Wno-tsan -mcmodel=medium -fPIC']
+tools.build:sharedlinkflags+=['-mcmodel=medium -fPIC']
+tools.build:exelinkflags+=['-mcmodel=medium -fPIC']
 {% endif %}
 
 {% elif compiler == "clang" %}
 
 {% if sanitizers == "Address" %}
 tools.build:cxxflags+=['-fsanitize=address,undefined,float-divide-by-zero,signed-integer-overflow,unsigned-integer-overflow
--fno-omit-frame-pointer -fno-var-tracking-assignments -O1 -mcmodel=medium']
-tools.build:sharedlinkflags+=['-mcmodel=medium']
-tools.build:exelinkflags+=['-mcmodel=medium']
+-fno-omit-frame-pointer -fno-var-tracking-assignments -O1 -mcmodel=medium -fPIC']
+tools.build:sharedlinkflags+=['-mcmodel=medium -fPIC']
+tools.build:exelinkflags+=['-mcmodel=medium -fPIC']
 {% elif sanitizers == "Thread" %}
 tools.build:cxxflags+=['-fsanitize=thread,undefined,float-divide-by-zero,signed-integer-overflow,unsigned-integer-overflow
--fno-omit-frame-pointer -fno-var-tracking-assignments -O1 -mcmodel=medium']
-tools.build:sharedlinkflags+=['-mcmodel=medium']
-tools.build:exelinkflags+=['-mcmodel=medium']
+-fno-omit-frame-pointer -fno-var-tracking-assignments -O1 -mcmodel=medium -fPIC']
+tools.build:sharedlinkflags+=['-mcmodel=medium -fPIC']
+tools.build:exelinkflags+=['-mcmodel=medium -fPIC']
 {% endif %}
 
 {% endif %}