diff --git a/cspell.config.yaml b/cspell.config.yaml
index ec0a522663..eeae3d12ff 100644
--- a/cspell.config.yaml
+++ b/cspell.config.yaml
@@ -112,6 +112,7 @@ words:
   - gpgcheck
   - gpgkey
   - hotwallet
+  - hwaddress
   - hwrap
   - ifndef
   - inequation
diff --git a/include/xrpl/basics/contract.h b/include/xrpl/basics/contract.h
index aba021b726..f41c272b61 100644
--- a/include/xrpl/basics/contract.h
+++ b/include/xrpl/basics/contract.h
@@ -1,5 +1,6 @@
 #pragma once
 
+#include <xrpl/basics/sanitizers.h>
 #include <xrpl/beast/type_name.h>
 
 #include <exception>
@@ -23,16 +24,28 @@ LogThrow(std::string const& title);
     When called from within a catch block, it will pass
     control to the next matching exception handler, if any.
     Otherwise, std::terminate will be called.
+
+    ASAN can't handle sudden jumps in control flow very well. This
+    function is marked as XRPL_NO_SANITIZE_ADDRESS to prevent it from
+    triggering false positives, since it throws.
 */
-[[noreturn]] inline void
+[[noreturn]] XRPL_NO_SANITIZE_ADDRESS inline void
 Rethrow()
 {
     LogThrow("Re-throwing exception");
     throw;
 }
 
+/*
+    Logs and throws an exception of type E.
+
+    ASAN can't handle sudden jumps in control flow very well. This
+    function is marked as XRPL_NO_SANITIZE_ADDRESS to prevent it from
+    triggering false positives, since it throws.
+*/
+
 template <class E, class... Args>
-[[noreturn]] inline void
+[[noreturn]] XRPL_NO_SANITIZE_ADDRESS inline void
 Throw(Args&&... args)
 {
     static_assert(
diff --git a/include/xrpl/basics/sanitizers.h b/include/xrpl/basics/sanitizers.h
new file mode 100644
index 0000000000..b954952848
--- /dev/null
+++ b/include/xrpl/basics/sanitizers.h
@@ -0,0 +1,13 @@
+#pragma once
+
+// Helper to disable ASan/HwASan for specific functions
+/*
+ ASAN flags some false positives with sudden jumps in control flow, like
+ exceptions, or when encountering coroutine stack switches. This macro can be used to disable ASAN
+ intrumentation for specific functions.
+*/
+#if defined(__GNUC__) || defined(__clang__)
+#define XRPL_NO_SANITIZE_ADDRESS __attribute__((no_sanitize("address", "hwaddress")))
+#else
+#define XRPL_NO_SANITIZE_ADDRESS
+#endif
diff --git a/src/libxrpl/basics/Number.cpp b/src/libxrpl/basics/Number.cpp
index 59a41157db..8bd048ae9e 100644
--- a/src/libxrpl/basics/Number.cpp
+++ b/src/libxrpl/basics/Number.cpp
@@ -258,7 +258,7 @@ Number::Guard::doRoundUp(
     }
     bringIntoRange(negative, mantissa, exponent, minMantissa);
     if (exponent > maxExponent)
-        throw std::overflow_error(location);
+        Throw<std::overflow_error>(std::string(location));
 }
 
 template <UnsignedMantissa T>
@@ -298,7 +298,7 @@ Number::Guard::doRound(rep& drops, std::string location)
             // or "(maxRep + 1) / 10", neither of which will round up when
             // converting to rep, though the latter might overflow _before_
             // rounding.
-            throw std::overflow_error(location);  // LCOV_EXCL_LINE
+            Throw<std::overflow_error>(std::string(location));  // LCOV_EXCL_LINE
         }
         ++drops;
     }