diff --git a/.github/scripts/conan/regenerate_lockfile.sh b/.github/scripts/conan/regenerate_lockfile.sh
new file mode 100755
index 000000000..2024c80d6
--- /dev/null
+++ b/.github/scripts/conan/regenerate_lockfile.sh
@@ -0,0 +1,25 @@
+#!/usr/bin/env bash
+
+set -ex
+
+TEMP_DIR=$(mktemp -d)
+trap "rm -rf $TEMP_DIR" EXIT
+
+echo "Using temporary CONAN_HOME: $TEMP_DIR"
+
+# We use a temporary Conan home to avoid polluting the user's existing Conan
+# configuration and to not use local cache (which leads to non-reproducible lockfiles).
+export CONAN_HOME="$TEMP_DIR"
+
+# Ensure that the xrplf remote is the first to be consulted, so any recipes we
+# patched are used. We also add it there to not created huge diff when the
+# official Conan Center Index is updated.
+conan remote add --force --index 0 xrplf https://conan.ripplex.io
+
+# Delete any existing lockfile.
+rm -f conan.lock
+
+# Create a new lockfile that is compatible with macOS.
+# It should also work on Linux.
+conan lock create . \
+    --profile:all=.github/scripts/conan/apple-clang-17.profile
diff --git a/.github/workflows/upload-conan-deps.yml b/.github/workflows/upload-conan-deps.yml
index 178e80d6c..dd31d3bc5 100644
--- a/.github/workflows/upload-conan-deps.yml
+++ b/.github/workflows/upload-conan-deps.yml
@@ -22,6 +22,7 @@ on:
 
       - .github/actions/conan/action.yml
       - ".github/scripts/conan/**"
+      - "!.github/scripts/conan/regenerate_lockfile.sh"
 
       - conanfile.py
       - conan.lock
@@ -32,6 +33,7 @@ on:
 
       - .github/actions/conan/action.yml
       - ".github/scripts/conan/**"
+      - "!.github/scripts/conan/regenerate_lockfile.sh"
 
       - conanfile.py
       - conan.lock
diff --git a/docs/build-clio.md b/docs/build-clio.md
index 51c6822b5..791bc49d3 100644
--- a/docs/build-clio.md
+++ b/docs/build-clio.md
@@ -97,30 +97,14 @@ Now you should be able to download the prebuilt dependencies (including `xrpl` p
 
 #### Conan lockfile
 
-To achieve reproducible dependencies, we use [Conan lockfile](https://docs.conan.io/2/tutorial/versioning/lockfiles.html).
+To achieve reproducible dependencies, we use a [Conan lockfile](https://docs.conan.io/2/tutorial/versioning/lockfiles.html).
 
 The `conan.lock` file in the repository contains a "snapshot" of the current dependencies.
 It is implicitly used when running `conan` commands, you don't need to specify it.
 
 You have to update this file every time you add a new dependency or change a revision or version of an existing dependency.
 
-> [!NOTE]
-> Conan uses local cache by default when creating a lockfile.
->
-> To ensure, that lockfile creation works the same way on all developer machines, you should clear the local cache before creating a new lockfile.
-
-To create a new lockfile, run the following commands in the repository root:
-
-```bash
-conan remove '*' --confirm
-rm conan.lock
-# This ensure that xrplf remote is the first to be consulted
-conan remote add --force --index 0 xrplf https://conan.ripplex.io
-conan lock create .
-```
-
-> [!NOTE]
-> If some dependencies are exclusive for some OS, you may need to run the last command for them adding `--profile:all <PROFILE>`.
+To update a lockfile, run from the repository root: `./.github/scripts/conan/regenerate_lockfile.sh`
 
 ## Building Clio